Research

Members

Funding

Theses

Awards

Publications

Collaborations

Equipment

News

Members

EDUCATION

PhD in Biochemistry and Molecular Biology (Faculty of Medicine, University of Ljubljana, Slovenia, 1996)
MSc in Biochemistry (Faculty of Chemistry, University of Ljubljana, Slovenia, 1993)
BSc in Chemistry (Faculty of Chemistry, University of Ljubljana, Slovenia, 1989)

PROFESSIONAL EXPERIENCE

Professor of Biochemistry and Molecular Biology, Faculty of Medicine, University of Ljubljana, Slovenia (2011-present)
Visiting Scholar, Helmholtz Zentrum München, Germany (2014-15, 3 months)
Visiting Professor, School of Medicine, University of Pennsylvania, Philadelphia, USA (2012-13, 4 months)
Associate Professor of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia (2006-11)
Visiting Scholar, School of Medicine, University of Pennsylvania, Philadelphia, USA (2001-02, 11 months)
Assistant Professor of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia (2001-06)
Postdoctoral Researcher, Genome Analysis Centre, GSF, Neuherberg, Germany (2000, 2 months)
Postdoctoral Researcher, Institute of Mammalian Genetics, GSF, Neuherberg, Germany (1997-98, 9 months)
Teaching Assistant, Faculty of Medicine, University of Ljubljana, Slovenia (1996-2001)
PhD student, Max-Planck Institute of Experimental Endocrinology, Hannover, Germany (3 months, 1995)

FELLOWSHIPS AND AWARDS

Zois Recognition for Outstanding Achievements (2022)
DAAD Fellowship (2014)
FULBRIGHT Research Award (2012)
Cobase Fellowship, National Research Council, USA (2001)
Postdoctoral Fellowship of the Slovenian Science Foundation (1998)
EMBO and DAAD Short-Term Fellowships (1997)
FEBS Short-Term Fellowship (1994)

MEMBERSHIP

Slovenian Biochemical Society
World Endometriosis Society
European Society of Gynecological Oncology
European Network for Individualized Treatment of Endometrial Cancer

EDITORIAL WORK

from 2022: Associate Editor of the Human Reproduction (I.F. 6.918)
from 2020: Section Board Member of International Journal of Molecular Sciences, section Molecular Endocrinology and Metabolism (I.F. 5.923)
from 2015: Associate Editor of Frontiers in Pharmacology, section Experimental Pharmacology and Drug Discovery (I.F. 5.81)
from 2015-2020: Associate Editor of the Journal Steroid Biochemistry and Molecular Biology (I.F. 4.292)
from 2009: Member of the Editorial Board of the Journal of Steroid Biochemistry and Molecular Biology

RESEARCH INTERESTS

Molecular basis of hormone-dependent diseases
Biomarkers
Metabolomics, proteomics, transcriptomics

SELECTED PUBLICATIONS

LANIŠNIK RIŽNER Tea, GJORGOSKA Marija. Steroid sulfatase and sulfotransferases in the estrogen and androgen action of gynecological cancers : current status and perspectives. Essays in Biochemistry. 2024, vol. 12, iss. ebc20230096, p. 1-13, doi: 10.1042/EBC20230096. [COBISS.SI-ID 202276355]

LANIŠNIK RIŽNER Tea, ROMANO Andrea. Targeting the formation of estrogens for treatment of hormone dependent diseases–current status. Frontiers in pharmacology. 2023. doi: 10.3389/fphar.2023.1155558. [COBISS.SI-ID 150180099]

PENNING M. Trevor, JONNALAGADDA Sravan, TRIPPIER C. Paul, LANIŠNIK RIŽNER Tea. Aldo-Keto Reductases and Cancer Drug Resistance. Pharmacological Reviews, 2021, 73:1-22, IF=25.68, doi: 10.1124/pharmrev.120.000122. [COBISS.SI-ID 67481603]

LANIŠNIK RIŽNER Tea, PENNING M. Trevor. Aldo-keto reductase 1C3 – assessment as a new target for the treatment of endometriosis. Pharmacological Research, 2019, Vol. 152, doi: 10.1016/j.phrs.2019.104446. [COBISS.SI-ID 34486233].

LANIŠNIK RIŽNER Tea, ADAMSKI Jerzy. Paramount importance of sample quality in pre-clinical and clinical research–Need for standard operating procedures (SOPs). Journal of Steroid Biochemistry and Molecular Biology, 2019, Vol. 186, 1-3, doi: 10.1016/j.jsbmb.2018.09.0174446. [COBISS.SI-ID 33951449]

Author's publication in PubMed and Scopus

TEACHING

Undergraduate courses (Faculty of Medicine, University of Ljubljana, Slovenia)

Concepts of biochemistry
Research in Medicine
Hormone-dependent gynecological and urological diseases: clinical and biochemical aspects
Biochemical markers
Biochemistry of steroids

Graduate courses (Interdisciplinary Doctoral Programme in Biomedicine, University of Ljubljana, Slovenia)

Steroid hormones and hormone-dependent diseases
Experimental methods for studying the biochemistry of steroid hormones

EDUCATION

PhD in Biochemistry and Molecular Biology (Faculty of Medicine, University of Ljubljana, Slovenia, 2005)
MSc in Biochemistry and Molecular Biology (Faculty of Medicine, University of Ljubljana, Slovenia, 2003)
MPharm (Faculty of Pharmacy, University of Ljubljana, Slovenia, 2001)

PROFESSIONAL EXPERIENCE

Reasearch Fellow, Faculty of Medicine, University of Ljubljana, Slovenia (2017–present)
Assistant Professor of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia (2012–2017)
Visiting Researcher, Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, USA; (March–April 2010)
Postdoctoral Researcher, Helmholtz Zentrum München, German Research Center for Environmental Health, Institute for Experimental Genetics, Neuherberg, Germany (2008, 10 months)
Visiting Researcher, Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, USA; (February 2008)
Visiting Researcher, Laboratory of Bacterial Envelopes and Antibiotics, University Paris-Sud, Orsay, France (February 2007)
Visiting Researcher, Conway Institute, University College Dublin, Ireland (October 2006)
Visiting Researcher, Laboratory of Bacterial Envelopes and Antibiotics, University Paris-Sud, Orsay, France (March–April 2006)
Teaching Assistant, Faculty of Medicine, University of Ljubljana, Slovenia (2006-2012)
Visiting Scholar, Helmholtz Zentrum München, German Research Center for Environmental Health, Institute for Experimental Genetics, Neuherberg, Germany (November–December 2005)
PhD student, Helmholtz Zentrum München, German Research Center for Environmental Health, Institute for Experimental Genetics, Neuherberg, Germany (October 2002–April 2003, August 2003–October 2003, November–December 2004)

FELLOWSHIPS AND AWARDS

Lek Award “Prima rešitev 2012” (2013)
The Jožef Stefan Golden Emblem Prize Award for research accomplishments (2007)
Futurum Award for PhD research accomplishments (2006)
Krka Prize for PhD research accomplishments (2005)
WFS (World Federation of Scientists) Grant (2004–2005)
Krka Prize for MSc research accomplishments (2003)
FEBS Short-term Fellowship (2003)
DAAD Fellowship (2002-2003)
Zois Post-gradute Fellowship (2001–2003)

RESEARCH INTERESTS

Enzyme activity and inhibition
Models for predicting drug permeability

SELECTED PUBLICATIONS

CASSETTA Alberto, STOJAN Jure, KRASTANOVA Ivet, KRISTAN Katja, BRUNSKOLE ŠVEGELJ Mojca, LAMBA Doriano, LANIŠNIK RIŽNER Tea. Structural basis for inhibition of 17β-hydroxysteroid dehydrogenases by phytoestrogens: The case of fungal 17β-HSDcl. The Journal of Steroid Biochemistry and Molecular Biology, 2017, 171: 80-93, doi: 10.1016/j.jsbmb.2017.02.020. [COBISS.SI-ID 33183449]

PETRUŠEVSKA Marija, HORVAT Matej, PETERNEL Luka, KRISTAN Katja. High-throughput automated dissolution method applicable for a wide dose range of controlled release pellets. Drug Development and Industrial Pharmacy, 2016, 42 (7): 1149-1157, doi: 10.3109/03639045.2015.1117485. [COBISS.SI-ID 1595996

ERDANI-KREFT Mateja, DRAGIN JERMAN Urška, LASIČ Eva, HEVIR-KENE Neli, LANIŠNIK RIŽNER Tea, PETERNEL Luka, KRISTAN Katja. The characterization of the human cell line Calu-3 under different culture conditions and its use as an optimized in vitro model to investigate bronchial epithelial function. European Journal of Pharmaceutical Sciences, 2015, 69: 1-9, doi: 10.1016/j.ejps.2014.12.017. [COBISS.SI-ID 1574236]

ERDANI-KREFT Mateja, DRAGIN JERMAN Urška, LASIČ Eva, LANIŠNIK RIŽNER Tea, HEVIR-KENE Neli, PETERNEL Luka, KRISTAN Katja. The characterization of the human nasal epithelial cell line RPMI 2650 under different culture conditions and their optimization for an appropriate in vitro nasal model. Pharmaceutical Research, 2015, Vol. 32, 665-679, doi: 10.1007/S11095-014-1494-0. [COBISS.SI-ID 1567580]

PETERNEL Luka, KRISTAN Katja, PETRUŠEVSKA Marija, LANIŠNIK RIŽNER Tea, LEGEN Igor. Suitability of isolated rat jejunum model for demonstration for BCS-based biowaiver request. Journal of Pharmaceutical Sciences, 2012, Vol. 101, 1436-1449, doi: 10.1002/jps.23027. [COBISS.SI-ID 1477468]

KRISTAN Katja, LANIŠNIK RIŽNER Tea. Steroid-transforming enzymes in fungi. Journal of Steroid Biochemistry and Molecular Biology, 2012, Vol. 129, 79-91, doi: 10.1016/j.jsbmb.2011.08.012. [COBISS.SI-ID 28853465]

Author's publication in PubMed.

TEACHING AND MENTHORSHIP

Undergraduate courses (Faculty of Medicine, University of Ljubljana, Slovenia)

Biochemistry (laboratory practical classes)

Supervision

Mojca BRUNSKOLE and Štefan STARČEVIĆ: New cinnammic acid derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase. 35th Krka Prizes (Undergraduate research work) Novo mesto: Krka, 2005. [COBISS.SI-ID 1824881]

JARC Tina. Determination of reference permeability coefficients for the biopharmaceutical classification system of active substances on Caco-2 cell model (Undergraduate theses) Ljubljana: [T. Jarc], 2013. [COBISS.SI-ID 3531377]

ČUČEK Evelin. Development of a high-throughput automated dissolution method on automated pipettor (Undergraduate theses) Ljubljana: [E. Čuček], 2014. [COBISS.SI-ID 3624305]

EDUCATION

MSc in public health (London School of Hygiene and Tropical Medicine, University of London, UK, 2009)
PhD in biochemistry and molecular biology (Faculty of Medicine, University of Ljubljana, Slovenia, 2001)
MSc in Molecular Biology and Biochemistry (Faculty of Medicine, University of Ljubljana, Slovenia, 1998)
Diploma in Biology (Faculty of Biotechnology, Department of Biology, University of Ljubljana, Slovenia, 1995)

PROFESSIONAL EXPERIENCE

Biostatistician, Syneos Health (renamed from INC Research merger with InVentiv Health), Munich, Germany (2015-present)
Project Manager, INC Research, Munich, Germany (2015, 3 months)
Biostatistician, Faculty of Medicine, University of Ljubljana, Slovenia (2012-present, consultant)
Sr. Health Economist, INC Research, Munich, Germany (2011-14)
Visiting Scientist, Helmholtz Zentrum Muenchen, Germany (2007-10)
Free-lance consultant, Tunisia (2005-2006)
Postdoctoral Researcher, Faculty of Medicine, University of Ljubljana, Slovenia (2004-05)
Visiting Scientist, Chinese National Centre for AIDS/STD Control and Prevention, Beijing, PR China (2002-03)
Postdoctoral Researcher, Temasek Life Sciences Laboratory, Singapore (2001-02, 6 months)
Junior Researcher, Faculty of Medicine, University of Ljubljana, Slovenia (1995-2001)

RESEARCH INTERESTS

Hormone-dependent diseases
Metabolomics
Biomarkers

SELECTED PUBLICATIONS

VOUK Katja, RIBIČ-PUCELJ Martina, ADAMSKI Jerzy, LANIŠNIK RIŽNER Tea: Altered levels of acylcarnitines, phosphatidylcholines, and sphingomyelins in peritoneal fluid from ovarian endometriosis patients. J Steroid Biochem Mol Biol, 2016 May;159:60-9. doi: 10.1016/j.jsbmb.2016.02.023. Epub 2016 Feb 24. [COBISS.SI-ID 32502745]

KOCBEK Vida, VOUK Katja, BERSINGER Nick A, MUELLER Michael D, LANIŠNIK-RIŽNER Tea: Panels of cytokines and other secretory proteins as potential biomarkers of ovarian endometriosis. Journal of Molecular Diagnostics, 2015, Vol. 17, 325-334. doi: 10.1016/j.jmoldx.2015.01.006. [COBISS.SI-ID 31891673]

KNOLL Stefanie, MAIR Christoph, BENTER Ursula, VOUK Katja, STANDAERT Baudouin: Will vaccination against rotavirus infection with RIX4414 be cost-saving in Germany? Health Economics Review, 2013, Vol. 3, doi: 10.1186/2191-1991-3-27. [COBISS.SI-ID 31148761]

KOCBEK Vida, VOUK Katja, MUELLER Michael, LANIŠNIK-RIŽNER Tea, BERSINGER Nick A. Elevated glycodelin-A concentrations in serum and peritoneal fluid of women with ovarian endometriosis. Gynecological Endocrinology, 2013, Vol. 29, 455-459, doi: 10.3109/09513590.2013.769516. [COBISS.SI-ID 30458585]

VOUK Katja, HEVIR-KENE Neli, RIBIČ-PUCELJ Martina, HAARPAINTER G., SCHERB Hagen, OSREDKAR Joško, MÖLLER Gabriele, PREHN Cornelia, LANIŠNIK RIŽNER Tea, ADAMSKI Jerzy. Discovery of phosphatidylcholines and sphingomyelins as biomarkers for ovarian endometriosis. Human Reproduction, 2012, Vol. 27, 2955-2965, doi: 10.1093/humrep/des152. [COBISS.SI-ID 30025945]

Author's publication in PubMed.

TEACHING AND MENTHORSHIP

Undergraduate courses (Faculty of Medicine, University of Ljubljana, Slovenia)

Biochemistry (laboratory practical classes)

EDUCATION

PhD in Biology (Faculty of Science, University of Zagreb, Croatia, 2019)
Master of Experimental Biology: Physiology and Immunology (Faculty of Science, University of Zagreb, Croatia, 2011)
BSc in Biology (Faculty of Science, University of Zagreb, Croatia, 2008)

PROFESSIONAL EXPERIENCE

Postdoctoral Researcher, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana (October 2020–)
Postdoctoral Researcher, Division of Molecular Biology, Faculty of Science, University of Zagreb (October 2019 – October 2020)
PhD student and Research Assistanty, Division of Molecular Biology, Faculty of Science, University of Zagreb (October 2015 – October 2019)
Junior Researcher, Department of Histology and Embryology, School of Medicine, University of Zagreb (June 2014 – October 2015)

RESEARCH INTERESTS

Hormone-dependent diseases, tissue engineering, regenerative medicine

SELECTED PUBLICATIONS

VUKASOVIC Andreja, ASNAGHI A. Maria, PETAR KOSTESIC Petar, QUASNICHKA Helen, COZZOLINO Carmino, PUSIC Maja, HAILS Lauren, TRAINOR Nuala, KRAUSE Christian, FIGALLO Elisa, FILARDO Giuseppe, KON Elizaveta, WIXMERTEN Anke, MATICIC Drazen, PELLEGRINI Graziella, KAFIENAH Wael, HUDETZ Damir, SMITH Tim, MARTIN Ivan, IVKOVIC Alan, WENDT David. Bioreactor-manufactured cartilage grafts repair acute and chronic osteochondral defects in large animal studies. Cell Proliferation, 2019, Vol. 52, Iss. 6, doi: 10.3390/ma12060919.

PANEK Marina, ANTUNOVIC Maja, PRIBOLSAN Lidija, IVKOVIC Alan, GOTIC Marijan, VUKASOVIC Andreja, CAPUT MIHALIC Katarina, PUSIC Maja, JURKIN Tanja, MARIJANOVIC Inga. Bone tissue engineering in a perfusion bioreactor using dexamethasone-loaded peptide hydrogel. Materials, 2019, Vol. 12 doi: 10.1016/j.jsbmb.2017.02.015.

VIDIC-STRAC IVONA, PUSIC Maja, GAJSKI Goran, GARAJ-VRHOVAC Vera. Presence of phthalate esters in intravenous solution evaluated using gas chromatography–mass spectrometry method. Journal of Applied Toxicology, 2011, Vol. 33, Iss.3. doi: 10.1002/jat.1741.

Author's publication in PubMed.

TEACHING AND MENTHORSHIP

Laboratory courses for students of Molecular Biology in Stem Cell Biology (Division of Molecular Biology, Faculty of Science, University of Zagreb, 2015-2020)

Laboratory courses for students of Molecular Biology in Research Methods in Molecular Biology (Division of Molecular Biology, Faculty of Science, University of Zagreb, 2015-2020)

EDUCATION

MSc in Molecular Biology (University of Ljubljana, Slovenia)
MSc in Neuroscience (University Miguel Hernandez, Spain)
BSc in Biochemistry & Physiology (University Ss. Cyril and Methodius, Macedonia)

PROFESSIONAL EXPERTISE

Liquid chromatography & mass spectrometry, flow cytometry, electrophysiology, basic & advanced molecular biology techniques

FELLOWSHIPS AND AWARDS

KRKA special recognition for Master thesis; 2021
Sciex scholarship – MSACL course: Getting Started with Quantitative LC-MS/MS in the Diagnostic Laboratory; 2021
Severo Ochoa Excellence Fellowship – by Spanish National Research Council; 2017
University Ss. Cyril and Methodius, Faculty of Natural Sciences and Mathematics - best student of generation; 2016

RESEARCH INTERESTS

From homeostasis to oncogenesis & back to homeostasis

SELECTED PUBLICATIONS

GJORGOSKA Marija, LANIŠNIK RIŽNER Tea. Integration of androgen hormones in endometrial cancer biology. Trends in Endocrinology and Metabolism. 2022. doi: 10.1016/j.tem.2022.06.001. [COBISS.SI-ID 116172547]

GJORGOSKA Marija, LANIŠNIK RIŽNER Tea. Estrogens and the Schrödinger's cat in the ovarian tumor microenvironment. Cancers, 2021, Vol. 13., iss. 19, 1-18. doi: 10.3390/cancers13195011. [COBISS.SI-ID 79662851]